Defining Immune Responses in COVID-19 to Understand Susceptibility and Target Treatments

Predicting COVID-19 booster immunogenicity against future SARS-CoV-2 variants and the benefits of vaccine updates

D Cromer, A Reynaldi, A Mitchell, TE Schlub, JA Juno, AK Wheatley, SJ Kent, DS Khoury, MP Davenport

2024-12-01

The ongoing evolution of the SARS-CoV-2 virus has led to a move to update vaccine antigens in 2022 and 2023. These updated antigen..

Mucosal antibody responses following Vaxzevria vaccination

KJ Selva, P Ramanathan, ER Haycroft, CW Tan, LF Wang, LE Downie, SK Davis, RA Purcell, HE Kent, JA Juno, AK Wheatley, MP Davenport, SJ Kent, AW Chung

2023-11-01

Mucosal antibodies play a key role in protection against breakthrough COVID-19 infections and emerging viral variants. Intramuscul..

Circulating effector γδ T cell populations are associated with acute coronavirus disease 19 in unvaccinated individuals

A von Borstel, THO Nguyen, LC Rowntree, TM Ashhurst, LF Allen, LJ Howson, NE Holmes, OC Smibert, JA Trubiano, CL Gordon, AC Cheng, SJ Kent, J Rossjohn, K Kedzierska, MS Davey

2023-04-01

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes severe coronavirus disease 2019 (COVID-19) in a smal..

Predicting the efficacy of variant-modified COVID-19 vaccine boosters

DS Khoury, SS Docken, K Subbarao, SJ Kent, MP Davenport, D Cromer

2023-03-01

Booster vaccination for the prevention of Coronavirus Disease 2019 (COVID-19) is required to overcome loss of protection due to wa..

The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants

M Koutsakos, WS Lee, A Reynaldi, HX Tan, G Gare, P Kinsella, KC Liew, G Taiaroa, DA Williamson, HE Kent, E Stadler, D Cromer, DS Khoury, AK Wheatley, JA Juno, MP Davenport, SJ Kent

2022-07-12

Vaccination against SARS-CoV-2 protects from infection and improves clinical outcomes in breakthrough infections, likely reflectin..